Juan Dubrot (Group Leader) oversaw TIDE Model Development and Screening. While completing his PhD in tumor immunology in Spain, he fell in love with 4-1BB (and his wife Carmen). He went to the Alps for his postdoctoral research in Geneva, Switzerland before being exiled to Boston. Outside of lab, he enjoys cheering on the Celtics, child-proofing his apartment, unveiling the secrets of kalimotxo and hunting for a cheese that is acceptable to his European palate. Juan is now a Principal Investigator at Cima Universidad de Navarra in Pamplona, Spain. We really miss him.

Austin Ayer (Research Associate) studied biology at Stanford University and then came to the TIDE team after studying fisheries management in Mexico as a Fulbright Scholar. Austin spent his time in Boston attempting to clone vectors and eating a plethora of pastries at Tatte. Now, Austin is pursuing his MD at Duke University.

Thomas Davis (Associate Computational Biologist) studied molecular biology at the University of Connecticut. After a few years in wet labs, he fell to the computational dark side and joined the Nabavi lab where he used bioinformatic methods to investigate BRCA1/2 mutations in triple negative breast cancer. He enjoys picking up heavy things (and putting them down), and codes exclusively in Scratch. Now Tom works as a software engineer in Boston (but we hope he comes back someday).

Sarah Kate Lane-Reticker (Research Associate) worked with the Model Development team and was the self-appointed biographer of the first several TIDE cohort members. Her greatest accomplishment in lab has been the invention of the caliper-pen, which is guaranteed to increase mouse-measuring efficiency by at least 12 tumors per hour. In her free time, she enjoys hiking, consuming carbohydrates in various forms, and looking at boats. Sarah Kate is pursuing her Ph.D. at Harvard University, but still comes by to visit occasionally.

Peter Du (Associate Computational Biologist) studied the role of class I MHC in NMDAR regulation in Lisa Boulanger's Lab at Princeton. Now, Peter is the captain of the computational team working to elucidate the mechanisms of resistance and sensitivity to cancer immunotherapy. Sometimes he even sneaks into the wet lab to get the job done. Peter enjoys endorsing Python over R, playing video games, and eating good Chinese food. Peter is now pursuing his PhD in Cancer Biology at Stamford University.

Ian Kohnle (Research Associate) works on targets emerging from the TIDE screens. He is known throughout the lab (particularly in the unicellular organism community) for his militant approach to cell culture and the exceptional anti-contamination standards to which he holds himself. He spends his non-working hours safeguarding his home against rodents and contemplating the state of world politics.

Gargi Mishra (Research Associate) worked with the Model Development team to engineer syngeneic mouse models for genome editing. She graduated from Mount Holyoke College with a bachelors in Biochemistry, and studied the role of macrophages in pregnancy during her undergrad. Gargi is now pursuing her MD/PhD at SUNY Upstate.

Arpit Panda (Associate Computational Biologist) worked alongside Peter to wrangle the many complex datasets that TIDE generated to discover shared and novel dependencies in cancer immunotherapy. Arpit is enrolled in the MD/PhD program at the University of Chicago.

Max Pass (Research Associate) studied Biological Chemistry at the University of Chicago, where he worked on tumor immunology research within the Gajewski Lab. At TIDE, he validates targets identified by the screens and elucidates mechanisms of immunotherapy sensitization. When not at the bench, Max can be found at loud, experimental concerts, or in his kitchen, weakly attempting to reproduce ethnic cuisines. Max is currently pursuing a PhD at UCSF.

Connor Antonio Richterich (Rotating Master’s Student in Molecular Health Science from ETH Zürich) Previously studied cell signaling in human keratinocytes using engineered optogenetic FGF receptors at the Sabine Werner lab. As part of TIDE, Connor optimized CRISPR-a screens to identify novel pro- and anti-phagocytosis signals on human macrophages. Connor is now working on his Ph.D. in the Schumacher lab at the Netherlands Cancer Institute.

Emily Robitschek (Research Associate) works primarily with the Target Validation team of TIDE to characterize hits that sensitize tumors or make them more resistant to immunotherapy. She loves dancing, learning about philosophy and psychology, and exploring Boston by bike with friends (although not so much in the wintertime). Emily is now working as a computational biologist in David Liu’s Lab.

Emily Schneider (Research Associate) studied Chemical & Biological Engineering at Princeton University. On TIDE, she works with the Target Validation team to explore screen hits and determine their mechanism of action. Outside the lab, you can find her catching up with friends, crafting bad puns, or scheming ways to get back in a boat. Emily is now pursuing her MD/PhD at Harvard Medical School.

Margaret Zimmer (Research Associate) studied the mechanisms of actin cytoskeleton regulation under the guidance of Kenneth Campellone at the University of Connecticut, where she also played Division I Women’s Ice Hockey. She joined the TIDE team in 2016, and was a key contributor to both the PTPN2 and ADAR papers. Margaret is pursuing her PhD in Biological and Biomedical Sciences (BBS) program at Harvard University.

Clara Wolfe (Research Associate) studied biochemistry at the University of Rochester where she worked in the Ghaemmaghami lab researching the macroautophagy pathway. In her free time, Clara enjoys experimental baking, running around Boston, and finding excuses to spend more time outdoors. Clara is now pursuing her Ph. D at Johns Hopkins University

Arvin Iracheta-Vellve (Research Scientist) completed his PhD and NIH pre-doctoral fellowship in the Szabo lab at UMass Medical School, studying the role of innate immunity mediating cell death and inflammation in liver disease. Prior to doing research, he was a high school science teacher, where he learned as much from his students as they ever did from him. When he’s home, he loves building Batman-themed Legos with his little Padawans and drinking fine wine with his wife. Arvin is now a Senior Scientist at Astra Zeneca.

Kira Olander (Associate Computational Biologist) studied bioinformatics at Wheaton College (MA) studied bioinformatics at Wheaton College (MA) and heard about the legend that is Rob Manguso. She followed him to the Manguso Lab where she worked loudly and quite happily on the model development team. When she is not promoting Game of GNAR or talking about skiing, she likes to dabble in most outdoors-related activities. Kira is now working on her Ph.D. at the University of Washington (when she’s not skiing).

Maggie Sharma (Strategic Operations Project Manager) left her days of bench work to become a Project Coordinator for TIDE, which is a job few can describe (including herself) but she will leave no question unanswered (we hope). You can often find her accidentally dancing in the hallways, begging for iced coffee, and laughing hysterically at her own jokes. Maggie now works in Program Management at Alnylam nearby, but you can often find her crashing Manguso Lab events.

Kepler Mears (Research Associate) may or may not have worked in the lab. It’s impossible to tell, as his website bio privileges were revoked some time ago for one of his many infractions. Fortunately, we still get to see him in the hallways, as he is pursuing his Ph.D. in the Zhang lab, just a few floors away.

Andrea Rivera (Research Associate) completed her BS in Cell and Molecular Biology at the University of Puerto Rico, Río Piedras. She also minored in Women and Gender Studies, as well as Medical Humanities. Amongst other things, Andrea keeps busy by making lists and hoping she'll get through them by the end of the day (which never happens). Andrea worked with the TIDE screening team but is now a clinical project analyst at a local company.

Juliette Suermondt (Visiting Graduate Student) is a Biology of Disease student from Utrecht University, the Netherlands. Her previous research includes studying zebrafish heart regeneration at Hubrecht institute and pediatric T-ALL at Princess Máxima Center. In the Manguso lab, she worked with Nelson on CAR-T cells. In her free time, she likes to play field hockey, travel and roam through Boston trying to find good coffee. Juliette is completing her Ph.D. at the Karolinska Institutet.

Tyler Balon (Research Associate) is a Providence native and recent graduate of THE Ohio State University. After completing his B.S. in Systems and Behavioral Neuroscience, Tyler worked his hardest to find a lab that had nothing to do with what he studied during undergrad. When he's wasn’t working on the PTPN2 project, you could find him being an obnoxious Buckeyes fan, cycling egregious distances, or looking for a new victim on the racquetball courts. Tyler is getting his M.D. at the Ohio State University College of Medicine.

James Patti (Research Associate)  is from Newton Massachusetts. He just graduated from Tufts University with a degree in biology and a minor in biotechnology. He is a huge Boston sports fan and played baseball in college as well. James is pursuing his M.D. at Tufts Medical School.

Sean Carlisle (Research Affiliate) is an undergraduate student entering his senior year at the University of Massachusetts, Amherst studying biochemistry and molecular biology. At UMass, Sean is a member of the Arcaro lab studying the microbiome’s relationship to breast cancer. As part of TIDE, he is assisting Cong with her cancer immunotherapy research. In the outside world, you can find him searching Boston for his new favorite restaurant, telling himself he enjoys running on the beach, and getting far too immersed in movies. Sean is completing his B.S. in Biochemistry and Molecular Biology at UMass Amherst.

Kaiya Kozuma (Research Associate) Dude! Kaiya graduated from UCLA, where she studied Molecular, Cell and Developmental Biology with a minor in Global Health. When she is not working on the PLC team, she can be found reading, nursing her caffeine addiction, teaching yoga or getting lost without google maps. Kaiya is now working as a clinical coordinator in Portland.

Peter Allen (Research Associate) is originally from Brookline, MA. He recently graduated from the University of Pittsburgh with degrees in Biology, Computer Science, and Chinese. He's new to the world of research and only barely fits at the lab bench. Outside the office, Peter can be found painting, reading, or blocking other peoples' views at concerts.

Kyrellos Ibrahim (Research Associate) (aka Kyro) was born and raised in sunny Southern California where he completed his BA in Biochemistry at Claremont McKenna College and took the weather for granted. In the wild, he can be spotted getting lost on his bike, booking flights to and from California, and trying to become the new funniest and coolest member of the lab.